Arginext Science Library

REVIEWS

  • Cardiovascular Effects of L-arginine
  • Arginine "Requirement" for Individuals at Risk for Atherosclerosis
  • The Pathophysiology of Peripheral Arterial Disease: Rational Targets for Drug Intervention
  • Nitric Oxide Synthase: Role in the Genesis of Vascular Disease
  • Molecular Mechanisms and Therapeutic Strategies Related to Nitric Oxide
  • Does ADMA Cause Endothelial Dysfunction? (PDF)
  • L-arginine Consensus Statement

 

JOURNAL ABSTRACTS

  • Molecular Mechanisms and Therapeutic Strategies Related to Nitric Oxide
  • Nitric Oxide Synthase: Role in the Genesis of Vascular Disease
  • Biochemical Evidence for Impaired Nitric Oxide Synthesis in Patients with Peripheral Occlusive Disease
  • Aging Progressively Impairs Endothelium-Dependent Vasodilation in Forearm Resistance Vessels of Humans
  • Cigarette Smoking is Associated with Dose-Related and Potentially Reversible Impairment of Endothelium-Dependent Dilation in Healthy Young Adults
  • Correction of Endothelial Dysfunction in Coronary Microcirculation of Hyper Cholesterolaemic Patients by L-Arginine
  • Differential Inhibition of Human Platelet Aggregation and Thromboxane A2 Formation by L-Arginine in vivo and in vitro
  • The Pathophysiology of Peripheral Arterial Disease: Rational Targets for Drug Intervention
  • L-Arginine Induces Nitric Oxide-Dependent Vasodilation in Patients with Critical Limb Ischemia. A Randomized, Controlled Study
  • Long-Term L-Arginine Supplementation Improves Small-Vessel Coronary Endothelial Function in Humans
  • Effect of Supplemental Oral L-Arginine on Exercise Capacity in Patients with Stable Angina Pectoris
  • Dietary L-Arginine Supplementation Normalizes Platelet Aggregation in Hypercholesterolemic Humans
  • A Health Bar Designed to Enhance Nitric Oxide Activity Restores Endothelium-Dependent Vasodilation in Hypercholesterolemia

 

CLINICAL STUDIES

  • Dietary L-Arginine Supplementation Normalizes Platelet Aggregation in Hypercholesterolemic Humans
  • Effect of Supplemental Oral L-Arginine on Exercise Capacity in Patients With Stable Angina Pectoris
  • Long-Term L-Arginine Supplementation Improves Small-Vessel Coronary Endothelial Function in Humans
  • L-Arginine Induces Nitric Oxide-Dependent Vasodilation in Patients with Critical Limb Ischemia. A Randomized, Controlled Study
  • Differential Inhibition of Human Platelet Aggregation and Thromboxane A2 Formation by L-Arginine in vivo and in vitro
  • Correction of Endothelial Dysfunction in Coronary Microcirculation of Hypercholesterolaemic Patients by L-Arginine
  • Cigarette Smoking is Associated with Dose-Related and Potentially Reversible Impairment of Endothelium-Dependent Dilation in Healthy Young Adults
  • Aging Progressively Impairs Endothelium-Dependent Vasodilation in Forearm Resistance Vessels of Humans
  • Biochemical Evidence for Impaired Nitric Oxide Synthesis in Patients with Peripheral Occlusive Disease
  • Improvement in Walking Distance and Quality of Life in Peripheral Arterial Disease by a Nutritional Product Designed to Enhance Nitric Oxide Activity
  • A Nutritional Product Designed to Enhance Nitric Oxide Activity Restores Endothelium-Dependent Function in Hypercholesterolemia
  • Randomized Trial of a Medical Food for the Dietary Management of Chronic, Stable Angina
  • Endothelial Dysfunction in Hypercholesterolemia is Reversed by a Nutritional Product Designed to Enhance Nitric Oxide Activity (PDF)
  • Nutritional Therapy for Peripheral Arterial Disease: A Double Blind, Placebo-Controlled, Randomized Trial of Arginext®

 

PRE-CLINICAL STUDIES

  • Elevated L-Arginine/Dimethylarginine Ratio Contributes to Enhanced Systemic NO Production by Dietary L-Arginine in Hypercholesterolemic Rabbits
  • Chronic Dietary Supplementation with L-Arginine Inhibits Platelet Aggregation and Thromboxane A2 Synthesis in Hypercholesterolaemic Rabbits in vivo
  • Asymmetric Dimethylarginine (ADMA): A Novel Risk Factor for Endothelial Dysfunction: Its Role in Hypercholesterolemia
  • Restoring Vascular Nitric Oxide Formation by L-Arginine Improves the Symptoms of Intermittent Claudication in Patients with Peripheral Arterial Occlusive Disease
  • Dietary L-Arginine Decreases Myointimal Cell Proliferation and Vascular Monocyte Accumulation in Cholesterol-Fed Rabbits
  • Dietary L-Arginine Reduces the Progression of Atherosclerosis in Cholesterol-Fed Rabbits: Comparison with Lovastatin
  • Supplementation of Hypercholesterolaemic Rabbits with L-Arginine Reduces the Vascular Release of Superoxide Anions and Restores NO Production
  • Cooke JP, Singer AH, Tsao P, Zera P, Rowan RA, Billingham ME. Antiatherogenic Effects of L-Arginine in the Hypercholesterolemic Rabbit
  • Arginine Restores Cholinergic Relaxation of Hypercholesterolemic Rabbit Thoracic Aorta
  • Effects of Dietary L-Arginine on Atherosclerosis and Endothelium-Dependent Vasodilatation in the Hypercholesterolemic Rabbit. Response According to Treatment Duration, Anatomic Site, and Sex
  • L-Arginine Reduces Human Monocyte Adhesion to Vascular Endothelium and Endothelial Expression of Cell Adhesion Molecules